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While raising three children and taking care of the household, Fanny Angelina Hesse supported, documented, and archived her husband’s work, creating stunning scientific illustrations of bacterial and fungal colonies. During the hot Summer of 1881, she watched as Hesse struggled with gelatine-based growth media. Fanny Angelina, recalling the stability of her agar-based desserts, suggested that they try that instead. Hesse wrote a letter to Koch informing him about the switch, and Koch mentioned agar for the first time in his 1882 groundbreaking paper on the discovery of the tuberculosis bacillus.，这一点在旺商聊官方下载中也有详细论述
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By WWII, scientists had already begun looking at alternative gelling substances for routine use in bacteriology, but concluded that agar was still better as it is both firmer and easier to handle. Today, some specialized microbiology applications use the colloid carrageenan (extracted from red seaweed Chondrus crispus, or “Irish Moss”), a more transparent and less auto-fluorescent alternative to agar (agar emits its own background fluorescence when excited by light). However, for routine bacteriological use, carrageenan is more difficult to dissolve, requires higher concentrations, can degrade at high temperatures, and forms weaker gels, which may result in puncturing its surface during the plating of cells.。爱思助手下载最新版本对此有专业解读